Sisa Minor is one of only two planets in the Sisa System, which is located only two light years from the border between the United Federation of Planets and the Syntan Republic. The other planet, Sisa Major, being unable to support life by a natural means, makes Sisa Minor the only habital planet in the system. The planet has a very dry climate characterized by extensive deserts, few surface water sources, and very few natural occuring plants and animals. Despite its harsh environment, the southern continent has a moderate population, consisting of mostly traders, nomads, and others involved in illeagal activities.

The planet's main settlement, New Las Vegas, is known as one of the most exotic and dangerous places in this part of the Federation, filled with gambling, drinking, and a large assortment of species from all over the galaxy. One of the most notable places in New Las Vegas is the Hotel Capone, which is the size of a small city. It remains one of the most popular privately held attractions in this sector, equipped with luxuries and anemities of all sorts. Despite the presence of citizens from all over the Federation, there is a general mistrust and hatred of Starfleet and other Federation officials in all the settlements on the planet. Most of the residents wish to be left alone so that they may conduct their illegal affairs in private.

Although Sisa is a federation planet, the United Federation of Planets excercises a limited oversight on this region of space. There is a local government in place, however it is plagued by corruption and suseptible to bribery. This makes the local government hardly a match for the dozens of illeagal operations going in and out of the Sisa System. It is even believed by Starfleet Intelligence that recently the Sisa System is the center of a smuggling operation between the Federation and the Syntan Republic. Intelligence also believes a large underground black market may exist in the bowels of New Las Vegas.